Round-table Meeting 2 February 2017

Dear CNAP member

Following of our successful round table discussion in December 2016, we are delighted to invite you to the next meeting of the classical pain concepts, which will take place on February 2nd, 2017 (12:30-15:00, Fredrik Bajers Vej 7A, A1-112: Loungen - behind the canteen). 

The goal of the round-table discussions is to gather interested individuals and consolidate central knowledge, theory, phenomena and explore key emerging developments within pain principles.To achieve this goal, classical pain concepts will be discussed four times annually. Followed by each round-table discussion there will be a social gathering. This time it will be flavored by the “Fastelavn”.

In this round-table, the concept of the ‘Pain Neuromatrix’ will be of focus. The notion of the ‘Pain Neuromatrix’ is an explanatory model. Ronald Melzack initially developed this model that involves two broad components: 1) pain is not produced by putative tissue damage (peripheral nervous system), but rather by the central nervous system, i.e., the brain and spinal cord; 2) various parts of the brain and spinal cord work in combination to produce multiple aspects of pain experience. The significance of the neuromatrix model of pain is to advance our understanding of the nature of pain and also therapies that target the central nervous system. It is however also fair to note that the ‘Pain Neuromatrix’ concept has been challenged recently. Attached you can find some papers related to the topic.

You are expected to have read the four selected papers (cf. program). Please prepare arguments in favour and against the pain neuromatrix concepts – please consider that you may be invited for a pro or cons panel.

Program

12.30
Welcome/short introduction to the CNAP round-table discussion

Presentation of selected papers

• “Phantom Limbs, the self and the brain (the d.o. hebb memorial lecture)” by Suzan (15 min)
• “The Cerebral Signature for Pain Perception and Its Modulation” by Gabriela (10 min)
• Questions/clarification (5 min)

13.05
Pitch of all incoming papers (1 min for each paper/participant)
Why choosing this particular paper?

Short break

13.30
Presentation of selected papers

• “The pain matrix reloaded a salience detection system for the body” by Carsten (15 min.)
• “Peripheral nervous system origin of phantom limb pain” by Jeppe (15 min.)

14.00                 
Debate (directed)
All participants prepare a selection of arguments in favour and against (pro/cons) the pain neuromatrix concepts.

14.30
Social event

15.00
Thank you for today!

INCOMING PAPERS
 

1. Phanton limbs and the concept of a neuromatrix
2. Reorganization of the motor cortex is associated with postural control deficits in recurrent low back pain
3. Motor Cortex Stimulation for Pain Relief: Do Corollary Discharges Play a Role?
4. The Cerebral Signature for Pain Perception and Its Modulation (selected for presentation)
5. Pain
6. Brain Mapping-Based Model of Δ9-Tetrahydrocannabinol Effects on Connectivity in the Pain Matrix
7. Analysis of synchrony demonstrates ‘pain networks’ defined by rapidly switching, task-specific, functional connectivity between pain-related cortical structures
8. Peripheral nervous system origin of phantom limb pain (selected for presentation)
9. Cerebral metabolism before and after external trigeminal nerve stimulation in episodic migraine
10. Central nervous system mechanisms of pain in fibromyalgia and other musculoskeletal disorders: behavioral and psychologic treatment approaches
11. Potentiation of sensory responses in the anterior cingulate cortex following digit amputation in the anaesthetised rat
12. Congenital insensitivity to pain: an update
13. Phantom limbs and the concept of a neuromatrix
14. A multisensory investigation of the functional significance of the “pain matrix"
15. Shape shifting pain: chronification of back pain shifts brain representation from nociceptive to emotional circuits
16. Painful peripheral states and sympathetic blocks
17. Phantom Limbs, the self and the brain (selected for presentation)
18. Neural correlates of heterotopic facilitation induced after high frequency electrical stimulation of nociceptive pathway